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Macular Hole

Angioid Streaks

Gyrate Atrophy

Age related macular degeneration

Best's disease

Retinitis Pigmentosa

Stargardt's disease

Myopic degeneration

Cone dystrophy

Retinal pigment epithelium hypertrophy

Retinitis pigmentosa and hemorrhagic retinopathy

Acute Zonal Outer Retinopathy, Annular Overt Type

Acute Idiopathic Exudative polymorphous Vitelliform Retinopathy

Idiopathic Choroidal Neovascularization

North Carolina Macular Dystrophy

Asteroid Hyalosis

Idiopathic Central Serous Chorioretinopathy

Bull's -Eye Macular Lesion

Autosomal Dominant Pattern Dystrophy of the RPE

 

 

Macular Hole.

Decreased  vision  , typically around the 6/60 for a full thickness hole ,More commonly, middle aged women are affected.

 

Critical Signs

A round , red spot in the center of the  macula usually from one third to two thirds of a disc diameter in size , surrounding by a gray halo ( marginal retinal detachment) . 

Notice  the loss of the normal foveolar depression and a yellow spot  in the center of the  hole.

 

 

 

 

 

 

 

 

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Best's disease.

( Vitelliform Macular Dystrophy) 

 

Decreased vision or asymptomatic. Onset at birth, but may not be detected until years later.

 

Critical signs

Yellow round , sub retinal lesions likened to an egg yolk or in some cases to a psudohypopyon ( see the pictures )  . Typically bilateral   and   located in the fovea  , measuring approximately one to two disc in size. Normal eletroretinogram (ERG) abnormal, elecrtrooculogram ( EOG) 

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 Retinitis Pigmentosa.

 Symptoms  

Difficulty with night vision and  loss of peripheral vision are most common .Poor central vision .

 

Critical Sign 

Classically , clumps of pigment arising from the photoreceptor layer  dispersed  throughout  the  peripheral retina in a perivascular pattern , often assuming a " bone spicule " arrangement .

 

 

 

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 Stargardt's disease.

Usually bilateral decreased vision in childhood or young adulthood .

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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Cone dystrophy.

Symptoms 

Slowly progressive bilateral visual  loss, photophobia, and poor color vision .

Vision is worse during the day than at night.

 

 

Critical Signs 

Bull's eye macular appearance or central geographic atrophy of the  retinal pigment epithelium ( RPE) and choriocapillaries.

Abnormal cone function on the eletroretinogram (ERG) . 

 

 

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Retinal pigment epithelium hypertrophy.

 

 -Grouped -type congenital pigmented nevi of the retinal pigment epithelium,(bear tracks)

Pigment spots that are often arranged in groups to resemble the footprints of animals, They are usually grouped in one sector of the fundus 

 

 

 -Retinal Nevus Halo,

 RPE hypertrophy with surrounding white halo.

 

 

 

 

 

 

 

 

 

 

 

 

 

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Retinitis pigmentosa and hemorrhagic retinopathy. 

This myopic patient male , 45 years old, complaining of deteriorated  vision , Note the retinitis pigmentosa , hemorrhagic and exudative maculopathy, and  atrophy of the iris - rt eye .

 

Algorafi eye clinic reported two cases with similar picture.

 

 

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Acute Zonal Outer Retinopathy, Annular Overt Type.

In this left eye fluorescein angiography showed evidence of acute RPE damage but no evidence of involvement of choriocapillaries,

The patient expressed scotomas in the visual field .

 

 

 

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Acute Idiopathic Exudative polymorphous Vitelliform Retinopathy.

 

Multiple pale,round,oval,

yellow-white lesions at the  level of the retinal pigment epithelium

The lesions are due to depigmentation rather than destruction  of the retinal pigment epithelium.

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Idiopathic Choroidal Neovascularization.

The age of this patient was 25 , female

Once you see choroidal Neovascularization like this lesion you would say it is the exudative form of the age related macular degeneration 

 

The age of this patient made the diagnosis of the idiopathic choroidal Neovascularization  ( macular type) .

 

The patient's V/A was less than 6/60 .

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North Carolina Macular Dystrophy.

 

a-rt b-lt fundus photography     in  female patient loosing her central vision , 

Note the irregular white subretinal scar in addition to several drusen in the rt eye, and Note the disciform atrophy of the retinal pigment epithelium in the lt eye  , Over hanging small staphylomatous lesions.

 

 

 

 

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Asteroid Hyalosis.

 

It is a degenerative disease of the vitreous of unknown cause .It is characterized by the development of white or yellow white spherical bodies composed of calcium soap within the collagen framework of the vitreous.  

 

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Idiopathic Central Serous Chorioretinopathy.

 

It is a  specific disease causing disciform macular detachment

The photograph showed the diffusion of the dye from the Choriod into the sub-RPE space and then into the subretinal space through a break. 

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Bull's-Eye Macular Lesion.  

 

The bull's maculopathy can be associate with the following :

-Age-related macular degeneration( ARMD).

-Stargardt's disease.

-Cone Dystrophy.

-Cholorquine retinopathy .

-Spielmeyer-Vogt syndrome.

 

 

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Autosomal Dominant Pattern Dystrophy of the RPE.

 

Characterized by the development ,usually in midlife , of mild disturbances of central vision associated with a variety of patterns of deposits of yellow,orange,or gray pigment in the macular area.

 

Based on the pattern of pigment distribution , pattern dystrophies have subdivided into at least four principles groups .A few patients  will show any combination  of all four of the patterns of fundus change described as following  

1- adult -onset foveomacular Vitelliform dystrophy.

2- butterfly-shaped pigment dystrophy.

3-reticular dystrophy of the RPE.                                                  

4-multifocal pattern dystrophy simulating fundus flavimaculatus.

5-coarse pigment mottling in the macula ( Fundus Pulverulentus). the fundus pictures  mostly represent this group. 

 

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